Published:
Baker, T.B., Hatsukami, D.K., Lerman C., O'Malley S.S., Shields,
A.E., & Fiore M.C. (2003). Transdisciplinary science applied
to the evaluation of treatments for tobacco use. Nicotine and
Tobacco Research, 5(Supplement 1): p. S89-S99.
Brunzell, D.H., Russell, D.S. & Picciotto, M.R. (2003). In
vivo nicotine treatment regulates mesocorticolimbic CREB and extracellular
regulated kinase signaling in C57B1/6J mice. Journal of Neurochemistry,
84: 1431-1441.
Caldarone, B.J., George T.P., Zachariou, V. & Picciotto,
M.R. (2000). Gender differences in learned helplessness behavior
are influenced by genetic background. Pharmacol. Biochem. Behav.,
66(4): 811-7.
Caldarone, B.J., Duman, C.H. & Picciotto, M.R. (2000). Fear
conditioning and latent inhibition in mice lacking the high affinity
subclass of nicotinic acetylcholine receptors in the brain. Neuropharmacology,
39(13): 2779-84.
Caldarone, B.J., Karthigeyan, K., Harrist, A., Hunsberger, J.G.,
Wittmack, E., King, S.L., Jatlow, P., & Picciotto, M.R. (2003).
Sex differences in response to oral amitriptyline in three animal
models of depression in C57BL/6J mice. Psychopharmacology, 170:94-101.
Cooney, J.L., Cooney, N.L., Pilkey, D.T., Kranzler, H.R., &
Oncken, C.A. (2003). Effect of nicotine deprivation on urges to
drink and smoke in alcoholic smokers. Addiction, 98:913-921.
Dudas, M.M., Sacco, K.A., & George, T.P. (2003). Psychopharmacological
treatments for nicotine addiction in schizophrenia. Essential
Psychopharmacology, 5(3):171-184.
Falba, T., Jofre-Bonet, M., Busch, S., Duchovny, N., & Sindelar,
J. (2004). Reduction of quantity smoked predicts future cessation
among older smokers. Addiction , 99: 93-102.
Fujita, M., Seibyl, J., Vaupel, D., Tamagnan, G., Early, M.,
Zoghbi, S., Baldwin, R., Horti, A., Koren, A., Mukhin, A., Khan,
S., Bozkurt, A. , Kimes, A, London, E., & Innis, R. Whole
body biodistribution, radiation-absorbed dose and brain SPET imaging
with [123I]5-I-A-85830 in healthy human subjects. (2002). European
Journal of Nuclear Medicine, 29:183-190.
Fujita, M., Ichise, M., van Dyck, C.H., Zoghbi, S.S., Tamagnan,G.,
Mukhin, A.G., Bozkurt, A., Seneca, N., Tipre, D., DeNucci1, C.C.,
Iida, H., Vaupel, D.B., Horti, A.G., Koren, A.O., Kimes, A.S.,
London, E.D., Seibyl, J.P., Baldwin, R.M., & Innis, R.B. (2003).
Quantification of nicotinic acetylcholine receptors in human brain
using [123I]5-I-A-85380 SPET. European Journal of Nuclear Medicine
and Molecular Imaging, Vol. 30, No. 12.
Fujita M, Al-Tikriti, M.S., Tamagnan, G., Zoghbi, S.S., Bozkurt,
A., Baldwin, R.M., & Innis, R.B. (2003). Influence of acetylcholine
levels on the binding of a SPECT nicotinic acetylcholine receptor
ligand [123I]5-I-A-85380. Synapse, 48(3): 116-22.
George, T.P., & O'Malley, S.S., (2004). Current pharmacological
treatments for nicotine dependence. TRENDS in Pharmacological
Sciences, 25(1):42-8.
George, T.P., Verrico, C.D., Picciotto, M.R., & Roth, R.H.,
(2000). Nicotinic modulation of mesoprefrontal dopamine neurons:
pharmacologic and neuroanatomic characterization. Journal of Pharmacology
and Experimental Therapeutics, 295(1): 58-66.
George, T.P., Vessicchio, J.C., Termine, A., Sahady, D.M., Head,
C.A., Pepper, W.T., Kosten, T.R. & Wexler, B.E. (2002). Effects
of smoking abstinence on visuospatial working memory function
in schizophrenia. Neuropsychopharmacology, 26: 75-85
George, T.P., Vessicchio, J.C., Termine, A., Bregartner, T.A.,
Feingold, A., Rounsaville, B.J., & Kosten, T.R. (2002). A
placebo-controlled trial of bupropion for smoking cessation in
schizophrenia. Biological Psychiatry, 52: 53-61.
George, T. P., Vessicchio, J.C. (2002). Treating tobacco addiction
in schizophrenia: Where do we go from here? (commentary). Addiction,
97: 795-796.
George, T.P., Seyal, A.S., Dolan, S.L., Dudas, M.M., Termine,
A., Vessicchio, J.C. (2002). Smoking and schizophrenia: An approach
to assessment and treatment. Primary Psychiatry, 9(11): 48-53.
George, T.P., Vessicchio, J.C., Termine, A. (2003). Nicotine
and tobacco use in schizophrenia. In: Medical Illness in Schizophrenia
(eds: Meyer, J.M. and Nasrallah, H.A.), American Psychiatric Press,
Inc., Washington, D.C., pp.81-98.
George, T.P., Vessicchio, J.C., Termine, A., Jatlow, P.I., Kosten,
T.R., & O'Malley, S.S. (2003). A preliminary placebo-controlled
trial of selegiline hydrochloride for smoking cessation. Biological
Psychiatry, 53:136-143
George, T.P., Picciotto, M.R., Verrico, C.D., & Roth, R.H.
(2001). Effects of nicotine pre-treatment on dopaminergic and
behavioral responses to conditioned fear stress in rats: Dissociation
of biochemical and behavioral effects. Biological Psychiatry,
49(3): 300-306.
George, T.P. (2002). Addiction in the 21st century: New problems,
novel approaches, innovative treatments (guest editorial). Psychiatric
Times, 19(2): 45.
Grady, S.R., Meinerz, N.M., Cao, J., Reynolds, A., Picciotto,
M.R., Changeux, J.-P., McIntosh, M.J., Marks, M.J. and Collins,
A.C. (2001). Nicotinic agonists stimulate acetylcholine release
from mouse interpeduncular nucleus: a function mediated by a different
nAChR than dopamine release from striatum. Journal of Neurochemistry,
76: 258-68.
Jamner, L., Whalen, C., Loughlin, S., Mermelstein, R., Audrain-McGovern,
J., Krishnan-Sarin, S., Worden, J., Leslie, F. (2003). Tobacco
use across the formative years: A road map to developmental vulnerabilities.
Nicotine and Tobacco Research, 5 Suppl 1: S71-8.
Jatlow, P., McKee, S., O'Malley, S. S. (2003). Correction of
urine cotinine concentrations for cotinine excretion: Is it useful?
Clinical Chemistry, 49: 1932-1934.
King, S.L., Marks, M.J., Grady, S.R., Caldarone, B.J., Koren,
A.O., Mukhin, A.G., Collins, A.C. & Picciotto, M.R. Conditional
expression in corticothalamic efferents reveals a developmental
role for nAChRs in modulation of passive avoidance behavior. Journal
of Neuroscience, 23(9): 3837-3843.
Krishnan-Sarin, S., Meandzija B. & O'Malley, S. (2003). Naltrexone
and nicotine patch in smoking cessation: A preliminary study.
Nicotine and Tobacco Research, 5:851-857.
Marks, M.J., Stitzel, J.A., Grady, S.R., Picciotto, M.R., Changeux,
J.-P. & Collins, A.C. (2000) Nicotinic-agonist stimulated
86Rb+ and [3H]epibatidine binding of mice differing in b2 genotype.
Neuropharmacology, 39(13): 2632-45.
Mukhin, A.G., Gundisch, D., Horti, A.G., Koren, A.O., Tamagnan,
G., Kimes, A.S., Chambers, J., Vaupel, D.B., King, S.L., Picciotto,
M.R., Innis, R. & London, E.D. (2000). 5-iodo-A-85380, &
a4ß2 subtype-selective ligand for nicotinic acetylcholine
receptors. Molecular Pharmacology, 57: 642-649.
McKee, S. A., Wall, A-M, Hinson, R. E. (2003). Effects of an
implicit mood prime on the accessibility of smoking expectancies
in college females. Psychology of Addictive Behaviors, Vol. 17,
No. 3, 219-225.
McKee, S. A., Maciejewski, P. K., Falba, T. & Mazure, C.
M. (2003). Sex differences in the effects of stressful life events
on changes in smoking status. Addiction, 98: 847-855.
Nash, J., Collins, B., Loughlin, S., Solbrig, M., Harvey, R.,
Krishnan-Sarin, S., Unger, J., Miner, C., Rukstalis, M., Shenassa,
E., Dube, C., Spirito, A. (2003). Training the transdisciplinary
scientist: A general framework applied to tobacco use behavior.
Nicotine and Tobacco Research, 5 Suppl 1: S41-53.
Olausson, P., Jentsch, J. D. & Taylor, J. R. (2003). Repeated
nicotine exposure enhances reward-related learning in the rat.
Neuropsychopharmacology, 28(7): 1264-71.
Owens, J.C., Balogh, S.A., McClure-Begley, T.D., Labarca, C.,
Lester, H.A., Picciotto, M.R., Wehner, J.M. & Collins, A.C.
(2003) a4b2*-type neuronal nicotinic receptors modulate the effects
of nicotine and ethanol on the acoustic startle response. Alcoholism
Clinical and Experimental Research, 27(12):1867-75.
Olausson, P. J., Jentsch, D., Taylor, J.R. (2004). Nicotine enhances
responding with conditioned reinforcement. Psychopharmacology,
171:173-178
Oncken, C., Prestwood, K., Cooney, J.L., Unson, C., Fall, P.,
Kulldorff, M., & Raisz, L. (2002). Effects of smoking cessation
or reduction on hormone profiles and bone turnover in postmenopausal
women. Nicotine & Tobacco Research, 4: 451- 458.
Oncken C.A., Kranzler, H., O'Malley, P., Gendreau, P., Campbell,
W.A. The effect of cigarette smoking on fetal heart rate characteristics.
Obstetrics and Gynecology, 2002;99:751-5.
Oncken, C.A., Henry, K.M., Campbell, W.A., Kuhn, C.M., Slotkin,
T.A., Kranzler, H.R. The effect of maternal smoking on fetal catecholamine
concentrations at birth. Pediatric Research, 2003;53:119-124.
Oncken, C.A., Kranzler, H.R. Pharmacotherapy for smoking cessation
during pregnancy. Drug and Alcohol Review 2003;22: 191-202.
Petry, N.M., Oncken, C. Cigarette smoking is associated with
increased severity gambling problems in treatment-seeking pathological
gamblers. Addiction 2002;97:745-53.
Picciotto, M.R. & Corrigall, W.A. (2002). Neuronal systems
underlying behaviors related to nicotine addiction: Neural Circuits
and Molecular Genetics. Journal of Neuroscience, 22(9): 3338-41.
Picciotto, M.R., Brunzell, D.H., Zachariou, V., Stevens, T.R.,
King, S.L. & Caldarone, B.J. (2001). Nicotinic acetylcholine
receptor knockout mice: Physiological and behavioral phenotypes
and possible clinical implications. Pharmacology and Therapeutics,
92:89-108.
Picciotto, M.R., Brunzell, D.H., & Caldarone, B.J. (2002).
Effect of nicotine and nicotine receptors on anxiety and depression.
Neuroreport, 13(9): 1097-106.
Picciotto, M.R. (2003). Nicotine as a modulator of behavior:
beyond the inverted U. TRENDS in Pharmacological Sciences, 24:
493-499.
Picciotto, M.R. & Zoli, M. (2002). Nicotinic receptors in
dementia and aging. Journal of Neurobiology, 53(4): 641-655.
Picciotto, M.R., Caldarone, B.J., King, S.L. & Zachariou,
V. (2000). Nicotinic receptors in the brain: links between molecular
biology and behavior. Neuropsychopharmacology, 22:451-65.
Picciotto, M.R., Brunzell, D.H., Zachariou, V., Stevens, T.R.,
King, S.L. and Caldarone, B.J. (2001). Nicotinic acetylcholine
receptor knockout mice: Physiological and behavioral phenotypes
and possible clinical implications. Pharmacology and Therapeutics,
92:89-108.
Picciotto, M.R, Alreja, M. and Jentsch, J.D. (2002). Acetylcholine.
In: K.L. Davis, D. Charney, J.T. Coyle and C. Nemeroff, eds. Psychopharmacology:
The Fifth Generation of Progress. Philadelphia: Lippincott, Williams
& Wilkins, pp. 3-14.
Price, T.B., Krishnan-Sarin, S., & Rothman, D.L. Smoking
impairs muscle recovery from exercise. (2003). Am J Physiol Endocrinol
Metab, 285: E116-E122.
Staley, J., Krishnan-Sarin, S., Zoghbi, S., Tamagnan, G., Fujita,
M., Seibyl, J., Maciejewski, P., O'Malley, S., Innis, R. (2001).
Sex differences in [123I]ß-CIT SPECT measures of dopamine
and serotonin transporter availability in healthy smokers and
nonsmokers. Synapse, 41:275-284.
Stevens, T.R., Krueger, S.R., Fitzsimonds, R.M. and Picciotto,
M.R. (2003) Mechanism of cortical neuroprotection by nicotine
involves activation of calcineurin and inactivation of L-type
channels. J Neurosci, 23(31):10093-9.
Vessicchio, J.C., Termine, A. & George, T.P. (2002). Smoking
abstinence and panic attacks. Journal of Clinical Psychiatry,
63(7): 594-595.
Whiteaker, P. Marks, M., Grady, S.R., Lu, Y., Picciotto, M.R.,
Changeux, J.-P. & Collins, A.C. (2000). Pharmacological and
null mutation approaches reveal nicotinic receptor diversity.
European Journal of Pharmacology, 393: 123-35.
Zachariou, V., Calderone, B.J., Weathers-Lowin, A., George, T.P.,
Elsworth, J.D., Roth, R.H., Changeux, J.P., & Picciotto, M.
(2001). Nicotine receptor inactivation decreases sensitivity to
cocaine. Neuropsychopharmacology, 24:576-589.
Zoghbi, S., Tamagnan, G., Fujita, M., Baldwin, R.M., Amici, L.,
Tikriti, M.A., Amici, L., Seibyl, J., Innis, R. (2001). Measurement
of plasma metabolites of (S)-5-[123I]iodo-3-(2-azetidinylmethoxy)pyridine
(5-IA-85380), a nicotinic acetylcholine receptor imaging agent,
in nonhuman primates. (2001) Nuclear Medicine and Biology, 28:91-96.
(Note: The Yale TTURC grant number is P50-DA-13334. However,
some Yale TTURC papers also appear under grant number P50-DA-84733,
which is no longer being used.)
In Press:
Balogh, S.A. , Keller, J.J., Picciotto, M.R., Paylor, R., Booker,
T.K., Beaudet, A., Heinemann, S. & Wehner, J.M. (2004). Role
of neuronal nicotinic receptors in the effects of nicotine and
ethanol on contextual fear conditioning. Neuroscience, under revision.
Dolan, S.L., Sacco, K.A., Termine, A., Seyal, A.S., Dudas, M.M.,
Vessicchio, J.C., Wexler, B.E., George, T.P. (2004). Neuropsychological
Deficits are Associated with Smoking Cessation Treatment Failure
in Patients with Schizophrenia. Schizophrenia Research, in press.
Dudas, M.M., George, T.P. (2004). Non-nicotine Pharmacotherapies
for Nicotine Dependence. Essential Psychopharmacology, in press.
Duhig, A. M., Cavallo, D. A., McKee, S. A., & Krishnan-Sarin,
S. Daily patterns of alcohol, cigarette and marijuana use in adolescent
smokers and nonsmokers. Addictive Behaviors, in press.
Jacobsen, L.K., Souza, D.C., Mencl, W.E., Pugh, K.R., Skudlarski,
P., Krystal, J.H. Nicotine effects on brain function and functional
connectivity in schizophrenia, Biological Psychiatry, in press.
King, S.L., Caldarone, B.J. & Picciotto, M.R. Reduced anxiety-like
behavior in mice lacking b2 subunit containing nAChRs. Pharmacology,
Biochemistry & Behavior, under revision.
McKee, S. A., Rounsaville, D., Petrelli, P. & Hinson, R.
E. (in press). Subjective effects of smoking while drinking among
college students. Nicotine and Tobacco Research.
Olausson, P., Jentsch, J.D., & Taylor, J.R. (2004). Enhanced
responding for conditioned reward produced by intra-accumbens
amphetamine is potentiated after cocaine sensitization. Psychopharmacology,
accepted pending revision.
Potenza, M.N., Steinberg, M. A., McLaughlin, S. D., Wu, R., Rounsaville,
B. J., Krishnan-Sarin, S., George, T.P., & O'Malley, S. S.
(in press). Characteristics of tobacco-smoking problem gamblers
calling a gambling helpline. American Journal of Addictions.
Sacco, K.A., Bannon, K.L., George, T.P. (2004). Nicotinic Receptor
Mechanisms and Cognitive Function in Normal States and Neuropsychiatric
Disorders. J. Psychopharmacol., in press.
Salovey, P., & Williams-Piehota, P. (in press). Field experiments
in social psychology: Message framing and the promotion of health
protective behaviors. American Behavioral Scientist.
Salovey, P. (in press). Promoting prevention and detection: Psychologically
tailoring and framing messages about health. In R. Bibace, J.
Laird, K.D. Noller, & J. Valsiner (Eds.), Science and medicine
in dialogue: Thinking through particulars and universals. Westport,
CT: Greenwood Publishing.
Snyder, A., Falba, T.A., Busch, S.A., & Sindelar, J. (in
press). Are state legislatures responding to public opinion when
allocating funds for tobacco control programs? Special issue:
The Shifting Landscape: Tobacco Control and Prevention Five Years
after the Master Settlement Agreement" forthcoming Health
Promotion Practice (2004).
Steward, W. T., Schneider, T. R., Pizarro, J. & Salovey,
P. (in press). Need for cognition moderates responses to framed
smoking cessation messages. Journal of Applied Social Psychology.